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Table 3 Assessment of potential predictors of the composite of mortality and OTI in the overall population

From: Non-invasive respiratory support in SARS-CoV-2 related acute respiratory distress syndrome: when is it most appropriate to start treatment?

Variables

Univariate analysis

Multivariate analysis

HR

95% CI

p

HR

95% CI

p

Age

1.152

1.084–1.224

 < 0.001

1.147

1.076–1.222

 < 0.001

Sex

0.811

0.319–2.059

0.659

   

CCI

1.514

1.274–1.798

 < 0.001

0.907

0.610–1.351

0.632

Duration of disease pre-admission

0.908

0.804–1.024

0.116

   

D-dimer

1.000

1.000–1.000

0.278

   

LUS Score

0.939

0.829–1.064

0.326

   

CT Score

1.400

0.801–2.446

0.238

   

Conversion to NIV

0.135

0.048–0.377

 < 0.001

0.581

0.153–2.203

0.424

Days of ventilation

0.954

0.846–1.075

0.438

   

Continuous ventilation

0.046

0.006–0.355

0.003

0.031

0.003–0.328

0.004

  1. Statistically significant values in bold
  2. ARDS Acute Respiratory Distress Syndrome, CCI Charlson Comorbidity Index, CI Confidence Interval, CT Computed Tomography, HR Hazard Ratio, LUS Lung Ultrasound, NIV Non Invasive Ventilation, OTI orotracheal intubation, P/F PaO2/FiO2 rate