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Table 2 Interstitial lung disease (ILD) patients undergoing surgical lung biopsy (SLB)

From: Thoracic surgery in the non-intubated spontaneously breathing patient

Author

Year

Study type

Analgesia

No. of Pts.

Results

Diagnostic yield (%)

Pompeo et al. [19]

2013

PFS

EC: 20

IB: 10

NIVATS: 30

Technical feasibility correlated with DLCO

Excellent in 20

Good in 9

Satisfactory in 1

Postoperative morbidity 3.3%

97

Peng et al. [84]

2017

CS

LA

NIVATS: 43

Chest tube removal on operating table

Postoperative morbidity: 7%, no death

88.4

Pompeo et al. [83]

2019

CS (MC)

IB: 84

EC: 28

NIVATS: 112

Perioperative morbidity: 7.1%, no death

Mean hospital stay: 2.5 days

96

Kurihara et al. [26]

2020

CS

EC

NIVATS: 15

DLT-VATS: 29

Reduced surgical time in NIVATS: 32.5 vs. 50.8 (min)

Shorter length of hospital stay in NIVATS: 1 vs. 10 (days)

Significant more ILD worsening in DLT-VATS group (one death)

100

Kim et al. [87]

2020

REV (3 studies)

1. EC: 20

1. IB: 20

2. IV: 43

3. EC: 10

1. NIVATS: 40

2. NIVATS: 43

3. NIVATS: 10

EC/IB mainly used for pain control

IB has benefit in operation time and hospital stay

Low morbidity rates: 3.3–7.0%

82.5–100

Guerrera et al. [82]

2021

PSM

EC + LA

NIVATS: 66

DLT-VATS: 34

Lower postoperative morbidity in NIVATS 3.0% vs. 20.6%

Shorter length of hospital stay in NIVATS 3.1 vs. 6.7 (days)

Reduced surgical time in NIVATS 38 vs. 77 (min)

Reduced anaesthesiologic time in NIVATS 97 vs. 132 (min)

73

Grott et al

2022

PSM

EC

NIVATS: 40

DLT-VATS: 40

Faster postprocedural recovery after NIVATS

Postoperative acute exacerbation of ILD similar between groups

98.75

  1. No. of Pts. number of patients, PFS prospective feasibility study, EC epidural catheter, IB intercostal block, NIVATS non-intubated video assisted thoracic surgery, DLCO diffusion for carbon monoxide, CS case series, LA local anesthesia, MC multicenter, DLT-VATS double-lumen tube—video assisted thoracic surgery, PSM propensity score matching, REV review, IV intravenous anesthesia, ILD interstitial lung disease