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Table 1 Characteristics of COPDGene study participants

From: Increased chest CT derived bone and muscle measures capture markers of improved morbidity and mortality in COPD

Demographic (mean ± SD)

Mild to very Severe COPD (GOLD 1–4)

(N = 4248)

Smoking controls

No COPD (GOLD 0)

(N = 4116)

Non-smoking controls

(N = 104)

Age (years)

63.1 ± 8.6

56.7 ± 8.4

62.2 ± 9.4

Percent Male N (%)

2,393 (56.3)

2,194 (53.3)

32 (30.8)

Race N (%)

   

 Non-Hispanic White

3,296 (77.6)

2,422 (58.8)

97 (93.3)

 African American

952 (22.4)

1,694 (41.2)

7 (6.7)

Pack Years

51.4 ± 27.0

37.3 ± 20.2

–

Current Smoker N (%)

1,833 (43.1)

2,441 (59.3)

–

BMI (kg/m2) N (%)

   

 Underweight (< 18.5)

106 (2.5)

27 (0.66)

1 (0.96)

 Healthy Weight (18.5 ≤ BMI < 25)

1,369 (32.2)

1,029 (25.0)

31 (29.8)

 Overweight (25 ≤ BMI < 30)

1,435 (33.8)

1,530 (37.2)

38 (36.5)

 Obese (BMI ≥ 30)

1,338 (31.5)

1,530 (37.2)

34 (32.7)

Inhaled Corticosteroid Use N (%)

1,880 (45.0)

224 (5.5)

0 (0)

Severe Exacerbations N (%)

818 (19.3)

174 (4.2)

0 (0)

Number of Comorbidities N (%)

   

 0

1,374 (32.4)

1,965 (47.8)

49 (47.1)

 1–2

2,325 (54.8)

1,883 (45.8)

51 (49.0)

 3 + 

545 (12.8)

266 (6.5)

4 (3.8)

Percent Emphysema

11.7 ± 12.3

2.0 ± 2.5

1.7 ± 2.2

FEV1 Percent Predicted

57.6 ± 22.7

97.4 ± 11.4

102.7 ± 13.6

Six Minute Walking Distance (m)

377.2 ± 124.5

455.7 ± 106.3

513.0 ± 100.0

  1. BMI, body mass index; COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; SD, standard deviation