Skip to main content
Fig. 1 | Respiratory Research

Fig. 1

From: Prediction and prognosis of adverse maternal and foetal/neonatal outcomes in pulmonary hypertension: an observational study and nomogram construction

Fig. 1

Nomogram development and validation (Maternal mortality or heart failure). A The nomogram incorporates five variables, with points allocated according to the scale for each variable. A total score was awarded from the sum of the individual scores, and used to calculate the predicted probability of maternal mortality or heart failure. B (a, b) Calibration curves for the nomogram in the Development (a) and Validation (b) cohorts. The calibration plot illustrates the accuracy of the original prediction (“Apparent”: light dotted line) and bootstrap models (“Bias-corrected”: solid line) in predicting the probability of maternal mortality or heart failure. C (a, b) Decision curve analysis for the nomogram in the Development (a) and Validation (b) cohorts. The y-axis indicates the net benefit, which is the sum of the benefits (true positives) minus harm (false positives). The x-axis indicates the threshold probability. The red line represents the nomogram net benefit. The yellow and blue lines represent the hypotheses that all or no patients experienced maternal mortality or heart failure, respectively. D (a, b) Violin plot analysis compared the distribution of risk prediction probabilities for patients experiencing maternal mortality or HF versus those without maternal death or HF in the Development (a) and Validation (b) cohorts. Demonstration of a violin plot and the depicted data. The three lines within the plot show the 1st and 3rd quartiles and the median of the dataset; the violin body width indicates the density of data along the y-axis. The violin edges represent the minimum and maximum values of the dataset. HTN hypertension, HF heart failure, NT-proBNP N-terminal pro-brain natriuretic peptide, NYHA New York Heart Association, RF respiratory failure

Back to article page