Table 1 Characteristics of the discovery cohort
From: Altered fecal microbiome and metabolome in adult patients with non-cystic fibrosis bronchiectasis
HC (n = 37) | SP (n = 30) | AE (n = 31) | P values | P values | |
|---|---|---|---|---|---|
(HC vs. SP) | (SP vs. AE) | ||||
Age, years† | 45.89 ± 10.37 | 50.57 ± 11.78 | 47.55 ± 13.84 | 0.092 | 0.363 |
Gender‡ | |||||
Female | 25 (68%) | 16 (53%) | 15 (48%) | 0.234 | 0.699 |
Male | 12 (32%) | 14 (47%) | 16 (52%) | ||
BMI † | 24.24 ± 3.26 | 21.37 ± 2.38 | 21.25 ± 2.95 | 0 | 0.856 |
Smoking status‡ | |||||
Never smoker | 34 (92%) | 26 (87%) | 27 (87%) | 0.487 | 0.960 |
Ever smoker | 3 (8%) | 4 (13%) | 4 (13%) | ||
Medication | |||||
Oral / IV antibiotics‡ | N/A | 0 | 31 | ||
FEV1% predicted† | N/A | 73.26 ± 25.72 | 64.97 ± 21.08 | 0.173 | |
P. aeruginosa infection‡ | N/A | ||||
Yes | 17 (57%) | 11 (35%) | 0.097 | ||
No | 13 (43%) | 20 (65%) | |||
BSI score† | N/A | 6.10 ± 2.85 | 7.19 ± 4.14 | 0.235 | |
SGRQ score† | N/A | 21.07 ± 8.02 | 25.21 ± 10.34 | 0.100 |