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Table 1 Participant Characteristics, N = 324

From: Black carbon content in airway macrophages is associated with increased severe exacerbations and worse COPD morbidity in SPIROMICS

 

Mean ± SD or n (%)

Age, yrs

63.58 ± 8.78

Sex, n (% female)

134 (41.4%)

Race, n (% white)

260 (80.7%)

Education, n (% > HS grad)

223 (69.0%)

Annual Household Income

 

 <$35,000

116 (35.8%)

 $35,000 - $74,999

101 (31.2%)

 ≥$75,000

62 (19.1%)

 Decline to answer

45 (13.9%)

Body Mass Index, kg/m2

28.50 ± 5.07

Medication LABA/LAMA, n (%)

87 (27.1%)

Smoking (pack-years)

47.76 ± 22.46

FEV1, percent predicted

84.30 ± 18.96

Current Smoker, n (%)

143 (44.4%)

Urinary Cotinine, ng/mL

597.70 ± 851.23

VGDF, n (%)

142 (44.2%)

ICS, n (%)

69 (21.5%)

OCS, n (%)

2 (0.6%)

CAT score

12.31 ± 7.72

mMRC score

0.83 ± 0.82

SGRQ score

28.26 ± 19.34

ECSC

9.16 ± 3.49

6MWD, meters

432.99 ± 101.29

Any exacerbations in the prior 12mo, n (%)

51 (16.1%)

Severe exacerbations in the prior 12mo, n (%)

22 (6.9%)

Any exacerbations over 12mo follow-up, n (%)

36 (11.9%)

Severe exacerbations over 12mo follow-up, n (%)

8 (2.6%)

Sputum Cell Differential

 

 Neutrophil %

59.81 ± 21.77

 Macrophage %

37.37 ± 20.65

 Eosinophils %

0.98 ± 2.27

 Lymphocytes %

0.11 ± 0.24

 Basophils %

0.00 ± 0.03

 Bronchial epithelial cells %

1.94 ± 3.69

Asthma

 

 Never had asthma, n (%)

243 (75.0%)

 Diagnosed with asthma, n (%)

61 (18.9%)

 Don’t know if had asthma, n (%)

20 (6.2%)