From: Impact of sleep-related hypoventilation in patients with pleuroparenchymal fibroelastosis
Ā | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
HR [95% CI] | p-value | HR [95% CI] | p-value | |
Age | 1.00 [.97ā1.04] | .84 | Ā | Ā |
Smoking history | 1.11 [.47ā2.61] | .81 | Ā | Ā |
BMI | .74 [.65ā.85] | ā<ā.01 | .68 [.56ā.83] | ā<ā.01 |
Gender male | 1.02 [.42ā2.46] | .66 | Ā | Ā |
PaCO2 | 1.05 [1.02ā1.09] | ā<ā.01 | Ā | Ā |
HCO3ā | 1.23 [1.09ā1.38] | ā<ā.01 | Ā | Ā |
PtCO2 mean | 1.04 [1.01ā1.07] | .02 | Ā | Ā |
PtCO2 max | 1.03 [1.01ā1.06] | .01 | Ā | Ā |
%FEV1 | .98 [.95ā1.00] | .08 | Ā | Ā |
FEV1/FVC | 1.05 [1.00ā1.09] | .05 | Ā | Ā |
%VC | .96 [.94ā.99] | .01 | Ā | Ā |
%FVC | .96 [.94ā.99] | ā<ā.01 | Ā | Ā |
%TLC | .98 [.96ā1.00] | .05 | Ā | Ā |
%RV | .99 [.99ā1.00] | .14 | Ā | Ā |
%RV/TLC | 1.00 [.98ā1.02] | .92 | Ā | Ā |
%DLCO | .98 [.96ā.99] | .04 | Ā | Ā |
%DLCO/VA | .98 [.96ā1.00] | .10 | Ā | Ā |
KL-6 | 1.00 [.99ā1.01] | .52 | Ā | Ā |
GAP score stage | 1.5 [1.12ā2.02] | ā<ā.01 | 2.44 [1.09ā5.46] | .03 |
Flat chest idex | .01 [.01ā1.14] | .06 | Ā | Ā |
HOTā+āNPPV | 1.15 [.39ā3.43] | .08 | Ā | Ā |
SRH | 5.36 [1.94ā14.82] | ā<ā.01 | 4.84 [1.31ā17.93] | .02 |