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Table 2 Multivariate Cox proportional hazards regression analysis of the relationship between sRAGE and mortality in dexamethasone-treated patients

From: High levels of soluble RAGE are associated with a greater risk of mortality in COVID-19 patients treated with dexamethasone

 

Ln sRAGE

high sRAGE*

 

HR

95% CI

P

HR

95% CI

P

Unadjusted

2.18

1.03–4.60

0.041

4.57

1.27–16.40

0.020

Model 1

2.39

1.10–5.22

0.028

4.76

1.32–17.16

0.017

Model 2

2.31

1.10–4.85

0.026

4.54

1.22–16.94

0.024

Model 3

2.54

1.21–5.32

0.014

6.32

1.59–25.07

0.009

Model 4

2.16

1.01–4.61

0.046

4.25

1.11–16.25

0.035

  1. Model 1: multivariate model adjusted for age
  2. Model 2: model 1 additionally adjusted for COPD
  3. Model 3: model 2 additionally adjusted for cancer
  4. Model 4: model 2 additionally adjusted for NEWS2 ≥ 5
  5. *sRAGE > 3532 pg/mL