Fig. 4
From: PKD1 deficiency induces Bronchiectasis in a porcine ADPKD model
PKD1deficiency downregulated E-cadherin in lung epithelial cells. (A) Representative Western blot and its quantification analyses of p-p38 MAPK and p38 MAPK in 2-year-old pig lungs. (B) Immunofluorescence staining of β-tubulin and p-p38 MAPK in 2 years old pig airways. Scale bar: 50 μm. (C) Immunofluorescence staining of PC1 and E-cadherin in Control and PKD1KD H1299 cells. Scale bar: 100 μm. (D) Representative Western blot and its quantification analyses of p-p38 MAPK and p38 MAPK in Control and PKD1KD H1299 cells. n = 3. The bars represent the mean ± SD; N.S. means no significant; **P <0.01; ***P<0.001.