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Fig. 3 | Respiratory Research

Fig. 3

From: PKD1 deficiency induces Bronchiectasis in a porcine ADPKD model

Fig. 3

PKD1deficiency caused airway epithelial barrier dysfunction. (A) Immunohistochemical staining of E-cadherin in 2-year-old pig airways. Scale bar: 100 μm. (B) Real-time PCR analyses of E-cadherin and CTNNB1 in 2-year-old PKD1+/− pig lungs. n = 3. (C) Real-time PCR analyses of genes related to tight junctions in 2-year-old PKD1+/− pig lungs. n = 3. (D) Immunofluorescence staining of occludin in 2-year-old pig airways. Scale bar: 50 μm. The bars represent the mean ± SD; N.S. means no significant; **P < 0.01; ***P < 0.001.

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