Skip to main content

Table 1 The association of the sentinel variants in the FoxP1 gene with FEV1 and FVC

From: The FoxP1 gene regulates lung function, production of matrix metalloproteinases and inflammatory mediators, and viability of lung epithelia

SNP

 

Meta-analysis (FVC)

Meta-analysis (FEV1)

 

Major allele

Minor allele

β*

p

Direction†

β*

p

Direction†

rs35480566

C

T

0.022

1.25E−20

 + / + 

0.019

1.79e−16

 + / + 

rs1499894

A

G

0.022

1.82E−20

 + / + 

0.019

1.02e−16

 + / + 

  1. *The β represents the change in the Z-score for the spirometry variable
  2. †The direction of the association in the two cohorts (UK BioBank/SpiroMeta) separately
Back to article page

Respiratory Research

ISSN: 1465-993X

Contact us