From: Diagnostic and prognostic value of ventilatory power in pulmonary hypertension
Variables | Normal control (n = 177) | PH |  | ||
---|---|---|---|---|---|
Total (n = 502) | Non-CW (n = 310) | CW (n = 192) | P value# | ||
Age, years | 49 (37, 58) | 39 (29, 54)** | 41 (29, 54) | 37 (29, 55) | 0.541 |
Body mass index, kg/m2 | 23.2 (21.0, 25.1) | 22.9 (20.4, 25.4) | 23.0 (20.7, 25.6) | 22.6 (20.2, 24.8) | 0.101 |
Female, n (%) | 125 (70.6) | 332 (66.1) | 210 (67.7) | 122 (63.5) | 0.334 |
Etiology of PH | Â | Â | Â | Â | 0.542 |
  IPAH, n (%) | – | 300 (59.8) | 182 (58.7) | 118 (61.5) |  |
  CTEPH, n (%) | – | 202 (40.2) | 128 (41.3) | 74 (38.5) |  |
WHO FC |  |  |  |  | < 0.001 |
  I and II, n (%) | 141 (79.7) | 261 (52.0) | 184 (59.4) | 77 (40.1) |  |
  III and IV, n (%) | 36 (20.3) | 241 (48.0) | 126 (40.6) | 115 (59.9) |  |
NT-proBNP, ng/L | 117.2 (46.9, 325.0) | 993.7 (287.0, 2095.5)** | 752.2 (202.7, 1952.3) | 1328.5 (568.0, 2374.0) | < 0.001 |
6MWD, m | 462.1 ± 88.2 | 403.5 (330.0, 464.8)** | 414.0 (335.3, 473.3) | 394.0 (315.5, 446.5) | 0.044 |
Newly diagnosed, n (%) | – | 291 (58.0) | 178 (57.4) | 113 (58.9) | 0.752 |
Pulmonary diseases, n (%) | 17 (9.6) | 43 (8.6) | 22 (7.1) | 21 (10.9) | 0.135 |
  Respiratory tract infection | 5 (2.8) | 16 (3.2) | 9 (2.9) | 7 (3.6) |  |
  Bronchial asthma | 3 (1.7) | 3 (0.6) | 1 (0.3) | 2 (1) |  |
  Emphysema | 4 (2.3) | 8 (1.6) | 3 (1) | 5 (2.6) |  |
  Bronchiectasis | 2 (1.1) | 10 (2) | 5 (1.6) | 5 (2.6) |  |
  Bronchitis | 3 (1.7) | 6 (1.2) | 4 (1.3) | 2 (1) |  |
PH specific therapy | Â | Â | Â | Â | 0.962 |
  None, n (%) | – | 59 (11.8) | 38 (12.3) | 21 (10.9) |  |
  Monotherapy, n (%) | – | 315 (62.8) | 192 (61.9) | 123 (64.1) |  |
  Double, n (%) | – | 120 (23.9) | 75 (24.2) | 45 (23.4) |  |
  Triple, n (%) | – | 8 (1.6) | 5 (1.6) | 3 (1.6) |  |
Intervention$, n (%) | – | 120 (23.9) | 79 (25.5) | 41 (21.4) | 0.292 |