CC16 polymorphisms in asthma, asthma subtypes, and asthma control in adults from the Agricultural Lung Health Study

Table 4 Associations between CC16 polymorphisms and chronic bronchitis and wheeze in the ALHS (N = 3046)

Additive genetic model for the rs12270961 genotype coded as the dnumber of copies of the G allele; for the rs3741240 genotype, as the number of copies of the A allele; thus, ORs reflect a multiplicative change in odds per additional copy of the designated alleleMultivariable logistic regression model adjusted for age, gender, state, smoking status, and asthma status
*Chronic bronchitis defined as individuals with both chronic cough and phlegm. Chronic cough defined as having a cough on most days, for three consecutive months or more during the year for a duration of two years or more. Similarly, chronic phlegm defined as bringing up phlegm on most days for three consecutive months or more during the year, for a duration of two years or more
†Wheeze defined as having wheezing or whistling in your chest during the past 12 months or wheeze when exerting during the past 12 months

ISSN: 1465-993X