Table 1 Subject characteristics
From: Influence of COPD systemic environment on the myogenic function of muscle precursor cells in vitro
A. Muscle precursor cell donors | |||
|---|---|---|---|
CONTROLS (n = 4) | COPD Normal weight (n = 4) | COPD Low weight (n = 4) | |
Demographics | |||
Age, years | 64.7 ± 3.6 | 64.7 ± 3.2 | 69.5 ± 5.9 |
Gender (M/F, n) | 3/1 | 2/2 | 1/3 |
Body composition | |||
BMI, kg/m2 | 24.4 ± 2.1 | 26 ± 4.1 | 17.9 ± 0.6 ¶¶ |
FFMI, kg/m2 | 17 ± 0.9 | 16.9 ± 2.1 | 13.6 ± 1.2 ¶¶ |
Lung Function | |||
FEV1, % pred | 95 ± 9.3 | 34.7 ± 12.6** | 38 ± 19.8** |
FEV1/FVC, % | 84.5 ± 8.7 | 38.8 ± 13.8* | 43 ± 19.6* |
RV, % pred | 103.7 ± 7.1 | 190.3 ± 31.2* | 209.7 ± 84.2 |
TLC, % pred | 93.2 ± 8 | 107.3 ± 16.5 | 118.5 ± 23.6 |
RV/TLC, % | 39.7 ± 4.7 | 62.9 ± 3.2** | 66.2 ± 14.3* |
DLCO, % pred | 94.5 ± 5.3 | 42.7 ± 25.3 | 48.2 ± 26.1* |
B. Serum donors | |||
CONTROLS (n = 7) | SCOPD (n = 7) | AECOPD (n = 7) | |
Demographics | |||
Age, years | 61.8 ± 6 | 67.4 ± 10.5 | 67.4 ± 10.1 |
Gender (M/F, n) | 1/6 | 6/1 | 4/3 |
Body composition | |||
BMI, kg/m2 | 28.8 ± 3.9 | 23.8 ± 4.6 | 25.7 ± 3.7 |
Lung Function | |||
FEV1, % pred | 104.3 ± 11.5 | 43 ± 21.1*** | 35.2 ± 15.1*** |
FEV1/FVC, % | 85.5 ± 3.4 | 38.3 ± 12.2*** | 39.4 ± 7.8*** |