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Table 3 The relationship between amount of exercise and risk of myocardial infarction or stroke

From: Association between exercise and risk of cardiovascular diseases in patients with non-cystic fibrosis bronchiectasis

 

No. of patients

Myocardial infarction

Stroke

 

No. of events

IR (/1,000 PY)

aHR* (95% CI)

No. of events

IR (/1,000 PY)

aHR* (95% CI)

Non-exercisers

110,499

3,011

4.4

1 (Reference)

2,634

3.8

1 (Reference)

Overall exercisers

       

  < 500 MET-min/wk

11,112

302

4.3

0.91

(0.81–1.03)

287

4.1

0.99

(0.88–1.12)

  500–999 MET-min/wk

11,407

228

3.2

0.71

(0.62–0.82)

222

3.1

0.80

(0.69–0.91)

  ≥ 1000 MET-min/wk

32,824

692

3.4

0.76

(0.70–0.83)

602

3.0

0.76

(0.69–0.83)

P-value

   

< 0.001

  

< 0.001

Non-exercisers

110,499

3,011

4.4

1 (Reference)

2,634

3.8

1 (Reference)

New exercisers

       

  < 500 MET-min/wk

457

11

3.8

0.89

(0.49–1.61)

14

4.8

1.38

(0.82–2.33)

  500–999 MET-min/wk

2,384

58

3.8

0.92

(0.71–1.19)

35

2.3

0.66

(0.48–0.93)

  ≥ 1000 MET-min/wk

18,215

413

3.6

0.81

(0.73–0.90)

354

3.1

0.79

(0.71–0.89)

P-value

   

< 0.001

  

< 0.001

Non-exercisers

110,499

3,011

4.4

1 (Reference)

2,634

3.8

1 (Reference)

Exercise dropouts

       

  < 500 MET-min/wk

10,377

284

4.4

0.91

(0.81–1.03)

269

4.1

0.99

(0.87–1.12)

  500–999 MET-min/wk

7,520

142

3.1

0.66

(0.56–0.78)

158

3.4

0.83

(0.71–0.98)

  ≥ 1000 MET-min/wk

1,480

18

2.0

0.51

(0.32–0.81)

20

2.2

0.67

(0.43–1.04)

P-value

   

< 0.001

  

0.046

Non-exercisers

110,499

3,011

4.4

1 (Reference)

2,634

3.8

1 (Reference)

Exercise maintainers

       

  < 500 MET-min/wk

278

7

3.8

0.93

(0.44–1.94)

4

2.2

0.64

(0.24–1.71)

  500–999 MET-min/wk

1,503

28

2.9

0.68

(0.47–0.98)

29

3.1

0.82

(0.57–1.18)

  ≥ 1000 MET-min/wk

13,129

261

3.2

0.72

(0.64–0.82)

228

2.8

0.72

(0.62–0.82)

P-value

   

< 0.001

  

< 0.001

  1. *In the adjustment, age, sex, low income, smoking status, alcohol consumption, body mass index, hypertension, diabetes mellitus, dyslipidemia, asthma or COPD, and cancer were included
  2. IR incidence rate, PY person-years, aHR adjusted hazard ratio, CI confidence interval, MET metabolic equivalent of task, COPD chronic obstructive pulmonary disease
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Respiratory Research

ISSN: 1465-993X

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