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Table 1 Baseline characteristics and lung function of COPD and asthma

From: Long-term variability of impulse oscillometry and spirometry in stable COPD and asthma

 

COPD-All (N = 73)

COPD-GOLD1-2 (N = 23)

COPD-GOLD3 (N = 31)

COPD-GOLD4 (N = 19)

Asthma (N = 119)

P value

Age, year

62.68 ± 9.57

63.04 ± 10.19

63.65 ± 9.20

60.68 ± 9.62

49.86 ± 14.26

< 0.0001

M3-M1, month

6.1 (3.4–16.6)

6.1 (3.3–22.8)

8.4 (3.0–19.0)

4.9 (4.0–12.6)

4.9 (4.0–12.6)

 

BMI, kg/m2

22.81 ± 3.59

23.85 ± 3.60

22.72 ± 3.58

21.71 ± 3.41

23.48 ± 3.48

0.337

FVC, L

2.02 (1.66–2.65)

2.91 (2.07–3.50)

2.02 (1.58–2.47)

1.74 (1.57–2.09)

2.88 (2.40–3.73)

< 0.0001

FEV1, L

0.95 (0.72–1.29)

1.51 (1.26–1.87)

0.89 (0.73–1.09)

0.69 (0.57–0.75)

2.36 (1.86–2.82)

< 0.0001

MEF 50, L/s

0.42 (0.30–0.71)

0.90 (0.71–0.94)

0.39 (0.31–0.54)

0.30 (0.22–0.33)

3.17 (2.56–4.03)

< 0.0001

MEF 25, L/s

0.19 (0.14–0.25)

0.29 (0.22–0.35)

0.19 (0.12–0.21)

0.15 (0.11–0.19)

0.85 (0.52–1.17)

< 0.0001

MMEF 75/25, L/s

0.37 (0.26–0.58)

0.67 (0.60–0.80)

0.35 (0.26–0.41)

0.25 (0.20–0.29)

2.16 (1.37–2.89)

< 0.0001

R5, cmH2O/(L/s)

5.98 (4.64–7.64)

4.82 (4.06–6.77)

7.23 (5.55–8.51)

5.83 (4.60–7.21)

4.25 (3.13–5.11)

< 0.0001

R20, cmH2O/(L/s)

3.17 (2.68–3.79)

2.97 (2.72–3.64)

3.63 (2.86–4.61)

2.69 (2.10–3.48)

3.17 (2.56–4.03)

0.778

R5-R20, cmH2O/(L/s)

2.85 (1.89–3.9)

1.73 (0.94–3.01)

3.60 (2.60–4.03)

2.85 (2.48–4.04)

0.85 (0.31–1.59)

< 0.0001

AX, cmH2O/L

45.70 (21.87–61.19)

18.76 (8.16–31.44)

52.88 (40.08–72.50)

49.67 (31.88–75.15)

6.91 (3.03–12.99)

< 0.0001

Freq, 1/s

28.8 (22.49–36.34)

21.52 (16.47–27.10)

33.99 (28.47–38.09)

28.8 (25.85–39.99)

16.82 (13.52–22.14)

0.507

X5, cmH2O/(L/s)

− 4.57 (− 2.67–6.88)

− 1.89 (− 1.44–3.84)

− 5.82 (− 4.17–8.13)

− 5.99 (− 3.96–7.86)

− 1.44 (− 0.89–1.76)

< 0.0001

  1. The data are presented as mean ± SD, median (interquartile range). Age and BMI were analyzed by one-way ANOVA, post hoc comparison was analyzed by Bonferroni, Wilcoxon Mann–Whitney test was used for data that did not conform to normality of distributions. M3-M1 represents the month difference between the third and first follow-up; COPD = chronic obstructive pulmonary disease; GOLD = the Global Initiative for Chronic Obstructive Lung Disease; BMI = Body Mass Index; FVC = forced vital capacity; FEV1 = forced expiratory volume in 1 s; MEF = maximal expiratory flow; MMEF = maximum midexpiratory flow; R5 = R at 5 Hz; R20 = R at 20 Hz; AX = a low-frequency reactance area; Freq = resonant frequency; X5 = Xrs at 5 Hz; P value COPD versus asthma