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Table 1 Baseline characteristics of the subjects included

From: Combining single-cell RNA sequencing of peripheral blood mononuclear cells and exosomal transcriptome to reveal the cellular and genetic profiles in COPD

 

Dis1

Dis2

Dis3

Dis4

Dis5

Dis6

Con1

Con2

Con3

Con4

Gender

Male

Male

Male

Female

Male

Male

Female

Male

Male

Male

Age

61

60

64

62

38

70

54

59

53

47

BMI (kg/m2)

21.0

18.0

19.5

21.4

23.1

18.6

23.9

21.5

21.0

22.0

Smoke*

Yes

Yes

Yes

None

Yes

Yes

None

None

None

None

CAT

13

5

6

11

6

20

    

sNEU (%)

72.93

95.31

90.37

88.72

      

sLYM (%)

2.63

1.27

1.17

1.43

      

sMAC (%)

23.3

1.27

5.89

8.39

      

sEOS (%)

1.12

2.12

2.55

1.43

      

FVC (L/%)

3.76/93.1

3.44/93.2

3.01/82

1.83/75.9

3.81/93

     

FEV1 (L/%)

1.88/59

1.5/51.2

1.65/57.2

0.94/46.6

2.62/76

     

FEV1/FVC (%)

49.9

43.5

57.2

51.3

68.9

     

GOLD

2

2

2

3

2

     

bWBC (109/L)

8.30

6.79

7.06

8.47

6.74

     

bNEU (%)

64.3

52.6

58.5

68.7

62.5

     

bNEU#

5.33

3.57

4.13

5.82

4.21

     
  1. Dis disease, Con control, CAT COPD assessment test, BMI body mass index, sNEU sputum neutrophil, sLYM sputum lymphocyte, sMAC sputum macrophage, sEOS sputum eosinophil, FVC forced vital capacity, FEV1 forced expiratory volume in 1 s, GOLD global initiative for chronic obstructive lung disease, bWBC blood white blood cell, bNEU blood neutrophil
  2. *Including former and current smoker