A prediction model for hospital mortality in patients with severe community-acquired pneumonia and chronic obstructive pulmonary disease

Table 1 Risk factors associated with hospital mortality in training cohort

Risk factors	Univariate analysis		Multivariate analysis
Risk factors	OR (95% CI)	P	OR (95% CI)	P
Demographic characteristics
Age	1.022 (1.005, 1.039)	0.012	1.025 (1.003, 1.047)	0.025
Comorbidities
Diabetes	1.618 (1.052, 2.489)	0.028	1.974 (1.156, 3.371)	0.013
Chronic renal diseases	2.378 (1.242, 4.554)	0.009	2.708 (1.182, 6.204)	0.019
Chronic cardiovascular diseases	1.568 (1.047, 2.347)	0.029
Chronic cerebrovascular diseases	5.454 (1.506, 19.755)	0.010
Vital signs
Systolic blood pressure (mmHg)	0.979 (0.973, 0.985)	< 0.001	0.980 (0.972, 0.988)	< 0.001
Diastolic blood pressure (mmHg)	0.990 (0.980, 1.000)	0.047
Laboratory examinations
Fibrinogen (g/L)	1.375 (1.250, 1.512)	< 0.001	1.305 (1.153, 1.476)	< 0.001
IL-6 (pg/mL)	1.013 (1.010, 1.015)	< 0.001	1.012 (1.009, 1.014)	< 0.001
BUN (mmol/L)	1.081 (1.054, 1.109)	< 0.001	1.058 (1.024, 1.094)	0.001
Neutrophil (×10⁹/L)	1.025 (1.001, 1.050)	0.043
Creatinine (µmol/L)	1.002 (1.000, 1.004)	0.036
Myoglobin (ng/mL)	1.000 (1.000, 1.001)	0.041
Troponin T (ng/L)	1.002 (1.000, 1.004)	0.017
Glucose (mmol/L)	1.069 (1.023, 1.116)	0.003
Platelet (×10⁹/L)	0.998 (0.997, 1.000)	0.030
Lactate (mmol/L)	1.113 (1.017, 1.217)	0.019

Data were calculated using logistics regression model
OR odds ratio; 95% CI 95% confidence interval; IL-6 interleukin-6; BUN blood urea nitrogen

ISSN: 1465-993X