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Fig. 4 | Respiratory Research

Fig. 4

From: Effects of tocilizumab and dexamethasone on the downregulation of proinflammatory cytokines and upregulation of antioxidants in the lungs in oleic acid-induced ARDS

Fig. 4

ac Effects of TCZ and DEX on OA-induced changes in lung tissues according to relative mRNA expressions of TNF-α, IL-1β, and IL-6. Each bar with a vertical line represents the mean fold change ± SEM of 6 rats compared to the control group. OA significantly increased TNF-α, IL-1β, and IL-6 levels in lung tissues compared to the control group (P < 0.05). All experimental treatments markedly decreased the TNF-α, IL-1β, and IL-6 levels in the lung tissues compared to the OA group (P < 0.05). Different letters (a, b, c, d) above bars indicate statistical differences between groups according to Duncan’s multiple range test (P < 0.05). There is no statistically significant difference between groups marked with the same letters in a graph (P > 0.05)

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