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Table 3 Impact of ever WS exposure on lung function decline independent of current smoking, airway obstruction, and CMH status at baselinea

From: Wood smoke exposure affects lung aging, quality of life, and all-cause mortality in New Mexican smokers

Model

FEV1 (ml/s)

FEV1/FVC ratio (%)

Basic model

  

 WS exposure × years

− 4.3 (1.9)

− 0.094 (0.038)

 P value

0.024

0.015

Basic model + current smoker × years

  

 WS exposure × years

− 4.1 (1.9)

− 0.088 (0.038)

 P value

0.033

0.021

 Current smoker × years

− 4.4 (1.7)

− 0.101 (0.033)

 P value

0.0082

0.0026

Basic model + airway obstruction × years

  

 WS exposure × years

− 4.3 (1.9)

− 0.094 (0.039)

 P value

0.025

0.016

 Airway obstruction × years

− 2.9 (1.9)

− 0.113 (0.039)

 P value

0.14

0.0041

Basic model + CMH × years

  

 WS exposure × years

− 4.0 (1.9)

− 0.088 (0.038)

 P value

0.038

0.022

 CMH × years

− 5.4 (2.0)

− 0.097 (0.040)

 P value

0.0061

0.014

Basic model + current smoker × years + airway obstruction × years + CMH × years

  

 WS exposure × years

− 3.7 (1.9)

− 0.080 (0.037)

 P value

0.050

0.034

 Current smoker × years

− 3.9 (1.9)

− 0.102 (0.034)

 P value

0.023

0.0026

 Airway obstruction × years

− 7.2 (2.0)

− 0.279 (0.038)

 P value

0.0002

 < 0.0001

 CMH × years

− 3.1 (2.1)

− 0.024 (0.041)

 P value

0.13

0.56

  1. CMH chronic mucous hypersecretion, WS woodsmoke
  2. aLinear mixed effects model was used to assess the impact of ever WS exposure on lung function decline through including an interaction term between ever WS exposure and time in cohort (years). We included fixed effects for baseline age, BMI, height, smoking stats, and packyears, sex, and ethnicities, and random effects for intercept and time in cohort. Interactions terms for current smoking, airway obstruction, and CMH at baseline with time in cohort were added to test the independent components of ever WS exposure effects on decline of FEV1 and FEV1/FVC ratio. WS exposure, airway obstruction, and CMH were coded as binary variables. Time in cohort has year as the unit