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Table 1 Characterization of normal and AATD subjects

From: Cigarette smoke exposed airway epithelial cell-derived EVs promote pro-inflammatory macrophage activation in alpha-1 antitrypsin deficiency

Characteristic

Normal Individual (n = 6)

AATD Individual (n = 6)

Genotype

MM

ZZ

Plasma AAT (µM)

25.6 (20.4—35.0)

3.7 (2.9—5.8)

Age, Year

35.8 (22–48)

45 (36–62)

Male sex

3

2

FEV1%

98.3 (71–116)

73.5 (52–96.6)

Current smoker

None

None

Lung Disease

None

Emphysema (5/6)