Table 1 Characteristics of study population stratified by COPD vs controls (never smokers) N = 351
From: Relationships of serum CC16 levels with smoking status and lung function in COPD
COPD N = 245 | Control subjects (never smokers) N = 106 | p | |
|---|---|---|---|
Age (years), mean (SD) | 66.5 (8.3) | 62.7 (9.5) | < 0.001 |
Sex, N (%) | |||
Male | 240 (99.2%) | 102 (96.2%) | 0.07 |
Female | 2 (0.8%) | 4 (3.8%) | |
Race, N (%) | |||
White | 234 (97.1%) | 103 (97.2%) | 0.97 |
Other | 7 (2.9%) | 3 (2.8%) | |
Education, N (%) | |||
≤ High school | 123 (52.1%) | 34 (32.7%) | 0.001 |
> High school | 113 (47.9%) | 70 (67.3%) | |
BMI (kg/m2), median (IQR) | 29.0 (25.4–33.5) | 32.5 (28.2–35.7) | < 0.0001 |
Smoking status, N (%) | |||
Current | 73 (30.2%) | – | |
Former | 148 (61.2%) | – | |
Never | 21 (8.7%) | 106 (100.0%) | |
Pack-yearsa, median (IQR) | 34.0 (13.0–56.0) | 0 (0.0) | – |
FEV1 (% predicted), mean (SD) | 65.4 (20.5) | 89.8 (16.2) | < .0001 |
FVC (% predicted), mean (SD) | 83.0 (18.7) | 86.7 (15.5) | 0.07 |
FEV1/FVC, mean (SD) | 57.7 (11.0) | 77.9 (4.7) | < .0001 |
COPD GOLD stage, N (%) | |||
I | 62 (25.6%) | – | |
II | 129 (53.3%) | – | |
III | 36 (14.9%) | – | |
IV | 15 (6.2%) | – | |