Fig. 2
From: Relationships of serum CC16 levels with smoking status and lung function in COPD
CC16 levels are correlated with FEV1/FVC within COPD subjects (N = 245). A A box and whisker plot depicts distribution of serum CC16 level across COPD GOLD stages. The median is represented by a solid line and the box represents the interquartile range, whiskers are the minimum and maximum values. There is no difference by stage (ANOVA test using log CC16 level by GOLD stages, p = 0.25). B Scatter plot depicts a weak positive correlation between FEV1/FVC and log CC16 level in subjects with COPD (r = 0.15, p = 0.02). Adjusted p-value from multiple linear regression model included the following covariates: age, pack-years, smoking status (current, former, never), assay plate number, BMI, and inhaled and systemic steroid use. r = Pearson correlation coefficient