Table 2 Top 20 transcriptomes differentially expressed between each cluster of asthmatics and non-asthmatics
From: Peripheral blood transcriptomic clusters uncovered immune phenotypes of asthma
Cluster 1 vs. Non-asthmatics | Cluster 2 vs. Non-asthmatics | Cluster 3 vs. Non-asthmatics | ||||||
|---|---|---|---|---|---|---|---|---|
Gene | Log2 fold change | q-value | Gene | Log2 fold change | q-value | Gene | Log2 fold change | q-value |
VSTM4 | 4.97 | 4.83 × 10–4 | VSTM4 | 4.62 | 1.21 × 10–5 | VSTM4 | 5.58 | 1.48 × 10–6 |
CCL23 | 2.58 | 4.83 × 10–4 | WDFY4 | − 3.90 | 3.11 × 10–11 | RPL36A | − 3.49 | 1.37 × 10–7 |
IL1RL1 | 2.05 | 9.16 × 10–4 | RP11-574F21.3 | − 3.90 | 5.80 × 10–8 | USP6 | − 3.50 | 1.37 × 10–5 |
PWP2 | − 23.78 | 5.83 × 10–12 | GOLGA8O | − 4.02 | 2.25 × 10–4 | CTAGE1 | − 3.51 | 8.35 × 10–4 |
|  |  |  | TREML4 | − 4.32 | 0.010 | ATP5L2 | − 3.57 | 9.03 × 10–4 |
|  |  |  | NCR3LG1 | − 4.39 | 3.39 × 10–9 | RNASEK-C17orf49 | − 3.61 | 0.010 |
|  |  |  | IFRG15 | − 4.54 | 2.29 × 10–4 | PAGE1 | − 3.65 | 0.002 |
|  |  |  | BIVM-ERCC5 | − 4.62 | 0.001 | RPL34 | − 3.67 | 4.16 × 10–7 |
|  |  |  | C7orf55-LUC7L2 | − 4.62 | 0.009 | RPEL1 | − 3.71 | 0.004 |
|  |  |  | RP11-603J24.9 | − 4.73 | 0.007 | RPL36A-HNRNPH2 | − 3.80 | 0.016 |
|  |  |  | GOLGA8R | − 4.83 | 2.22 × 10–6 | LPA | − 4.06 | 0.003 |
|  |  |  | AC007192.4 | − 4.89 | 0.036 | ZNF578 | − 4.22 | 1.09 × 10–6 |
|  |  |  | CTD-2370N5.3 | − 5.35 | 4.12 × 10–5 | WTH3DI | − 4.26 | 7.23 × 10–5 |
|  |  |  | COMMD3-BMI1 | − 5.67 | 0.002 | UQCRHL | − 4.39 | 8.03 × 10–11 |
|  |  |  | RP11-449H3.3 | − 5.68 | 5.94 × 10–5 | ATP5EP2 | − 5.06 | 1.76 × 10–7 |
|  |  |  | CH507-9B2.1 | − 6.97 | 1.92 × 10–4 | AC104534.3 | − 5.53 | 0.037 |
|  |  |  | TMEM189-UBE2V1 | − 7.11 | 1.54 × 10–8 | KCNE1B | − 5.84 | 0.003 |
|  |  |  | PWP2 | − 7.32 | 0.045 | CTD-3074O7.11 | − 6.61 | 0.016 |
|  |  |  | RP11-343C2.11 | − 8.14 | 8.46 × 10–18 | TREML4 | − 6.63 | 0.001 |
|  |  |  | FLJ20373 | − 8.47 | 3.48 × 10–10 | PWP2 | − 23.00 | 8.03 × 10–11 |