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Table 2 Analysis of variance on the three selected groups

From: Identification of COVID-19 patients at risk of hospital admission and mortality: a European multicentre retrospective analysis of mid-regional pro-adrenomedullin

 

Not admitted (n = 131; 20.2%)

Admitted without event (n = 421; 65.2%)

Admitted with event (n = 94; 14.6%)

P

Age (years)

51.0 ± 12.3

65.6 ± 14.3*

75.1 ± 10.6#°

 < 0.001

Male gender

67 (51.1%)

260 (61.8%)

56 (59.6%)

0.097

Creatinine (mg/dl)

0.79 [0.67–0.91]

0.95 [0.79–1.11]*

1.01 [0.8–1.46]#

 < 0.001

Platelets (/mmc)

236.79 ± 136.01

244.93 ± 108.65

215.55 ± 104.54

0.106

MR-proADM (nmol/L)

0.57 [0.48–0.70]

0.91 [0.70 -1.26]*

1.345 [0.98–2.22]#°

 < 0.001

WBC (/mmc)

5.30 [4.25–6.50]

6.24 [4.42–8.76] *

7.63 [5.20–11.04]#°

 < 0.001

Lymphocytes (/mmc)

1.20 [0.80–1.70]

0.88 [0.62–1.20]*

0.77 [0.47–1.05]#°

 < 0.001

LDH (U/L)

499 [418–621]

553 [418–694]*

735 [544–971]#°

 < 0.001

Procalcitonin (mg/dl)

0.05 [0.03–0.08]

0.07 [0.04–0.14]*

0.13 [0.07–0.45]#°

 < 0.001

CRP (mg/L)

20.10 [9.80–44.75]

59.45 [19.60–99.56]*

87.22 [48.27–149.70]#°

 < 0.001

D-Dimer (ng/ml)

493 [350–676]

640 [428–1132]*

969 [516–1777]#°

 < 0.001

Cardiovascular disease

4 (3.1%)

130 (30.9%)*

49 (52.1%)#°

 < 0.001

Chronic respiratory disease

8 (6.1%)

71 (16.9%)*

28 (29.8%)#°

 < 0.001

Diabetes

12 (9.2%)

28 (6.7%)

12 (12.8%)

0.125

Chronic kidney disease

0 (0.0%)

37 (8.8%) *

19 (20.2%)#°

 < 0.001

Malignancy

4 (3.1%)

43 (10.2%)

13 (13.8%)#

0.012

Hypertension

23 (17.6%)

209 (49.6%) *

59 (62.8%)#

 < 0.001

SOFA score

0 [0–1]

3 [2–4]*

4 [2–5]#°

 < 0.001

NEWS2 score

0 [0–0]

1 [0–3]*

2 [0–4]#

 < 0.001

  1. *: p < 0.05 post-hoc “not admitted” vs “admitted without event”; #: p < 0.05 post-hoc “not admitted” vs “admitted with event”; °: p < 0.05 post-hoc “admitted without event” vs “admitted with event”