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Table 2 Top 15 DEGs at 1 h, 4 h, and 24 h after whole cigarette smoke exposure

From: Early transcriptional responses of bronchial epithelial cells to whole cigarette smoke mirror those of in-vivo exposed human bronchial mucosa

Gene symbol logFC logCPM Adj. P-value FDR
1 h     
CYP1A1 5.69 8.73 1.23E−17 1.76E−13
ATF3 2.92 6.41 2.91E−16 1.39E−12
HMOX1 4.20 9.42 4.78E−16 1.71E−12
FOSB 3.16 4.71 8.43E−15 2.01E−11
KLF6 1.80 6.62 1.52E−14 3.10E−11
TIPARP 2.34 7.06 1.89E−14 3.38E−11
ZNF331 2.04 4.57 7.22E−14 1.15E−10
PER1 1.51 6.00 1.92E−13 2.74E−10
NR4A2 1.36 6.20 2.73E−13 3.55E−10
CYP1B1 2.70 8.93 3.27E−13 3.90E−10
SNHG3 -1.27 3.93 7.38E−13 8.12E−10
NR4A1 2.43 6.25 8.27E−13 8.45E−10
CBARP 2.64 2.00 1.41E−12 1.34E−09
OVOL1 1.65 3.56 1.70E−12 1.52E−09
RHOB 1.84 6.31 2.92E−12 2.46E−09
4 h     
TXNRD1 2.76 9.97 1.38E−32 1.97E−28
UNKL 2.70 5.80 2.72E−29 1.94E−25
GCLM 2.66 7.79 1.23E−26 5.87E−23
SQSTM1 2.47 10.51 1.80E−26 6.45E−23
STX3 1.28 6.34 4.49E−26 1.28E−22
ZNF469 3.62 5.31 1.38E−25 3.30E−22
SYNJ2 1.88 6.97 2.31E−25 4.71E−22
GSR 1.26 7.67 9.42E−25 1.68E−21
SLC12A7 1.56 7.84 2.02E−24 3.20E−21
HMOX1 8.16 9.42 5.57E−24 7.96E−21
GCLC 2.33 8.75 6.23E−24 8.10E−21
CYP1A1 9.16 8.73 3.97E−23 4.38E−20
AKR1C3 1.60 7.27 3.98E−23 4.38E−20
CYP4F3 2.75 6.02 1.15E−22 1.13E−19
OSGIN1 4.23 6.66 1.19E−22 1.13E−19
24 h     
FTL 1.38 9.38 9.49E−16 9.61E−12
G6PD 1.21 7.97 1.34E−15 9.61E−12
TFRC 1.52 7.39 2.38E−15 1.13E−11
CYP1A1 4.21 8.73 4.23E−14 1.21E−10
FTH1 1.30 10.70 9.39E−13 1.92E−09
CYP1B1 2.54 8.93 1.92E−12 3.04E−09
ALDOC 1.25 3.90 6.35E−12 7.57E−09
GPR37L1 1.38 2.82 2.44E−10 1.74E−07
KLF3.AS1 − 1.43 3.76 1.22E−09 7.26E−07
KLK6 1.99 1.88 1.76E−09 9.00E−07
NQO1 1.20 8.47 2.87E−09 1.37E−06
ALDH3A1 1.03 10.37 1.29E−08 4.86E−06
SERPINB4 1.78 5.46 2.60E−08 9.05E−06
PRKN − 1.39 1.04 2.98E−08 1.01E−05
AKR1B10 1.15 6.46 4.68E−08 1.49E−05
  1. logFC log fold change, logCPM log counts per million, adj. adjusted, FDR false discovery rate