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Fig. 4 | Respiratory Research

Fig. 4

From: Early transcriptional responses of bronchial epithelial cells to whole cigarette smoke mirror those of in-vivo exposed human bronchial mucosa

Fig. 4

Pathway and protein level analysis of DEGs after whole cigarette smoke exposure of primary bronchial epithelial cells differentiated at the air–liquid interface. GSVA analysis of A immediate early genes (IEGs), and genes associated with B activator protein-1 (AP-1), C aryl hydrocarbon receptor (AhR), D Nrf2, E ferroptosis pathways. F Kinetics of CXCL8 gene expression and CXCL8 protein level upon cigarette smoke exposure. The error bar indicates the standard deviation (n = 8). Gene sets which were significantly different after cigarette smoke exposure compared to Air (p < 0.05) are shown by the * symbol. **p < 0.01, ***p < 0.001

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