Predictive potential of ACE phenotyping in extrapulmonary sarcoidosis

Respiratory Research

Table 1 Patient characteristics

Sarcoidosis	(n = 89)	%	Other lung diseases	(n = 31)	%
Diagnosis (morphologically/clinically)	59/30
Gender, male/female	30/59	33.7/66.3	Gender, male/female	13/18	41.9/58.1
Age, years	48.7 (23–73)		Age, years	58.4 (27–88)
Male age, years	40.6 (23–65)		Male age, years	56.8 (27–74)
Female age, years	53.1 (25–73)		Female age, years	59.6 (32–88)
Organs involved:		%	Disease:		%
Lymph node	81	91.0	ILD	18	58.1
Lung	80	89.9	SjS	5	16.1
Skin	20	22.5	Chronic bronchitis	5	16.1
Spleen	12	13.5	IgG4-AD	2	6.5
CNS	11	12.4	Systemic scleroderma	1	3.2
Kidney	9	10.1	Allergic alveolitis	1	3.2
Eye	9	10.1	Amyloidosis	1	3.2
Heart	8	9.0	Bronchial asthma	1	3.2
Joint	7	7.9	ACE inhibitor use	0	0
Liver	5	5.6
Muscle	2	2.2
ACE inhibitor use	11	12.4

Bold values are mean values
Biopsies samples were available (and performed) from 59 patients. Other 30 patients obtained a diagnosis based on combined clinical criteria, such as results of chest CT, whole body PET-CT, laboratory tests, clinical manifestations and course of the disease. Age is shown as mean (extremes in range). Data are shown as mean (extremes in range) and number (%)
ILD interstitial lung disease, SjS Sjögren syndrome, IgG4-AD immunoglobulin G4-associated disease. Clinical characteristics of these patients are described in details in [38]

ISSN: 1465-993X