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Table 1 Study population characteristics and group comparison between patients weaned successfully and unsuccessfully

From: Diaphragm ultrasound evaluation during weaning from mechanical ventilation in COVID-19 patients: a pragmatic, cross-section, multicenter study

 

Population

Weaning failure

Weaning success

p-value

 

N = 57

N = 25

N = 32

 

Age [IQR]

65.0 [56.0; 71.0]

64.0 [57.0; 71.0]

66.5 [55.8; 71.0]

0.766

Sex (male, %)

42 (73.7%)

17 (68.0%)

25 (78.1%)

0.577

SAPS2

34.0 [31.0; 41.0]

34.0 [32.0; 41.0]

33.5 [31.0; 41.0]

0.612

RASS

− 1.00 [− 2.00; 0.00]

− 2.00 [− 2.00; − 1.00]

− 1.00 [− 2.00; 0.00]

0.031

KM score

2.00 [1.00;3.00]

2.00 [2.00;3.00]

1.00 [1.00;2.00]

0.002

SAP (mmHg)

133 [123; 149]

130 [123; 140]

140 [124; 151]

0.227

DAP (mmHg)

70 [63; 80]

68 [60; 73]

76 [65; 82]

0.096

HR (bpm)

78 [70; 90]

82 [73; 90]

77 [70; 90]

0.541

RR (bpm)

18 [16; 23]

22 [16; 24]

18 [16; 21]

0.302

Body Temperature (°C)

36.9 [36.5; 37.3]

36.9 [36.7; 37.2]

36.9 [36.5; 37.3]

0.389

SpO2 (%)

98 [96; 99]

98 [96; 99]

98 [96; 99]

0.915

FiO2

0.40 [0.35; 0.50]

0.45 [0.40; 0.50]

0.40 [0.35; 0.45]

0.033

pH

7.46 [7.43; 7.50]

7.47 [7.42; 7.49]

7.46 [7.43; 7.50]

0.955

PaCO2 (mmHg)

43.0 [38.0; 48.0]

43.0 [39.0; 48.0]

41.5 [38.0; 47.2]

0.562

PaO2 (mmHg)

85.0 [75.0; 106]

84.0 [72.0; 96.0]

92.0 [79.0; 115]

0.215

PaO2/FiO2 ratio (mmHg)

216 [164; 280]

176 [144; 231]

241 [183; 308]

0.032

Lactates (mEq/L)

1.10 [0.90; 1.40]

1.10 [0.90; 1.31]

1.10 [0.91; 1.43]

0.981

HCO3 (mEq/L)

30.2 [27.9; 32.7]

30.5 [27.9; 32.0]

29.9 [27.7; 32.9]

0.682

BE

6.70 [3.40; 8.90]

7.00 [3.40; 8.10]

6.45 [3.72; 9.00]

0.930

Diam exp. (mm)

1.90 [1.50; 2.50]

1.90 [1.50; 2.50]

1.85 [1.50; 2.52]

0.968

Diam insp. (mm)

2.40 [2.00; 3.20]

2.60 [2.00; 3.60]

2.40 [1.98; 3.20]

0.484

DTF (%)

28.0 [21.7; 38.9]

28.0 [16.7; 57.1]

27.6 [22.1; 37.0]

0.612

Previous NIV

46 (80.7%)

23 (92.0%)

23 (71.9%)

0.090

NIV Length (hours)

15.0 [3.00; 36.0]

20.0 [4.00; 36.0]

7.00 [0.00; 37.0]

0.248

Mech. Vent. duration (days)

14 [7; 22]

15 [8; 24]

13 [7; 22]

0.670

ICU LOS (days)

20.0 [12.0; 31.0]

27.0 [18.0; 37.0]

16.5 [10.0; 27.5]

0.025

Hospital LOS (days)

37.0 [28.0; 47.0]

44.0 [29.0; 51.0]

34.0 [26.8; 43.0]

0.171

  1. SAPS2 Simplified Acute Physiology Score 2, RASS Richmond Agitation-Sedation Scale, KM score Kelly–Matthay score, SAP Systolic Arterial Pressure, DAP diastolic arterial pressure, HR heart rate, RR Respiratory Rate, BT Body Temperature, BE Base Excess, Diam exp. Expiratory Diaphragmatic Diameter, Diam insp. Inspiratory Diaphragmatic Diameter, DTF Diaphragmatic Thickening Fraction, Previous NIV Non-Invasive Ventilation trial before invasive mechanical ventilation, NIV Length NIV trial duration, Mech. Vent. Length invasive mechanical ventilation duration, ICU LOS ICU Length of Stay, Hosp LOS Hospital Length of Stay