Fig. 6
Treatment with l-carnitine and baicalin attenuated neonatal hyperoxia-induced lung function decline in adult mice. C57BL/6 J mice (< 12 h old) were exposed to 95% O2 for 3 days, and allowed to recover in air until pnd14 and pnd60. Mice were treated with l-carnitine (LCT, 150 and 300 mg/kg, i.p.) and baicalin (BLN, 50 and 100 mg/kg, i.p.) daily between pnd4 and pnd13. Body weight were assessed at both pnd14 and pnd60 (A, B), while lung compliance and resistance were evaluated using the FlexiVent system at pnd60 (C, D). N = 5–10. **P < 0.01, ***P < 0.001 vs air. †P < 0.05, vs O2/veh group using one-way ANOVA followed by Tukey’s multiple comparison test