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Table 1 Baseline patient characteristics

From: Utility of bile acids in large airway bronchial wash versus bronchoalveolar lavage as biomarkers of microaspiration in lung transplant recipients: a retrospective cohort study

Characteristic

Patients (N = 61)

Median age (range)—years

59 (21–75)

Male sex—N (%)

35 (57)

Primary disease—N (%)

 

 Pulmonary fibrosisa

30 (49)

 Chronic obstructive pulmonary disease

12 (20)

 Cystic fibrosis

8 (12)

 Other

11 (18)

GERD diagnosed by 24-h esophageal pH-impedance probe—N (%)

17 (28)

On proton pump inhibitor—N (%)

56 (92)

Median time from reflux testing to bronchoscopy (range)—days

11 (1–265)

Median time from transplant to bronchoscopy (range)—months

3.02 (1.81–3.95)

Acute rejection (A) grade—N (%)

 

 A0

36 (59)

 A1 or higher

12 (20)

 AX or no biopsy performed

13 (21)

Lymphocytic bronchiolitis (B) grade—N (%)

 

 B0

29 (48)

 B1R

1 (2)

 BX or no biopsy performed

31 (51)

Positive BAL microbiological culturea—N (%)

11 (18)

Donor recipient CMV status—N (%)

 

 Donor−/Recipient−

14 (23)

 Donor−/Recipient + 

15 (25)

 Donor + /Recipient−

13 (21)

 Donor + /Recipient + 

19 (31)

  1. BAL bronchoalveolar lavage, CMV cytomegalovirus, GERD gastroesophageal reflux
  2. aOne patient had a diagnosis of sarcoidosis. One had hypersensitivity pneumonitis. The rest (twenty-eight patients) had idiopathic pulmonary fibrosis
  3. bIncludes pathogenic bacteria, acid-fast bacilli, fungi, and viruses