Table 3 Top differentially expressed genes in TNFα versus control in NT siRNA or CEBPD siRNA cells
From: CEBPD modulates the airway smooth muscle transcriptomic response to glucocorticoids
Gene symbol (gene name) | Ensembl ID | NT siRNA | CEBPD siRNA | ||||||
|---|---|---|---|---|---|---|---|---|---|
log2FC | Q-value | Mean normalized counts | log2FC | Q-value | Mean normalized counts | ||||
no TNFα | TNFα | no TNF | TNFα | ||||||
IL32 (interleukin 32) | ENSG00000008517 | 3.04 | 6.50E−118 | 284 | 2213 | 3.27 | 5.20E−189 | 237 | 2306 |
IL6 (interleukin 6) | ENSG00000136244 | 3.57 | 3.10E−80 | 892 | 11,217 | 3.56 | 8.50E−97 | 878 | 10,187 |
TNFAIP3 (TNF alpha induced protein 3) | ENSG00000118503 | 3.40 | 5.30E−79 | 901 | 9453 | 3.36 | 5.50E−27 | 916 | 9196 |
COL7A1 (collagen, type VII, alpha 1) | ENSG00000114270 | 1.40 | 1.90E−75 | 3896 | 10,229 | 1.60 | 7.70E−58 | 3237 | 9913 |
NFKB2 (nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)) | ENSG00000077150 | 2.13 | 2.70E−70 | 666 | 2909 | 2.26 | 1.90E−86 | 515 | 2463 |
IER3 (immediate early response 3) | ENSG00000137331 | 1.95 | 1.70E−50 | 1141 | 4313 | 1.89 | 3.50E−83 | 797 | 2903 |
ICAM1 (intercellular adhesion molecule 1) | ENSG00000090339 | 3.20 | 2.20E−24 | 490 | 4243 | 3.45 | 1.00E−68 | 268 | 2715 |