Fig. 2
From: CEBPD modulates the airway smooth muscle transcriptomic response to glucocorticoids
CEBPD knockdown influenced ASM expression of genes in the IL-6 receptor signaling pathway. A Expression levels of IL6R, SOCS3, SOCS1, and SOCS2 in response to control, BUD, TNFα, and BUD + TNFα exposures in NT siRNA and CEBPD siRNA transfected cells obtained with RNA-Seq data show that CEBPD knockdown altered their response to BUD, TNFα and/or BUD + TNFα exposure. Boxplots show the median value at the center line, the box spans the inter-quartile range, and the whiskers span the minimum and maximum (without outliers) of normalized read counts (N = 3–4 donors per condition). Individual read count values are displayed as points. B IL-6 receptor signaling pathway diagram indicating known relationships among IL-6R, SOCS and STAT3 proteins. BUD budesonide, NT non-targeting