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Fig. 3 | Respiratory Research

Fig. 3

From: PTPRO knockdown protects against inflammation in hemorrhage shock-induced lung injury involving the NF-κB signaling pathway

Fig. 3

Down-regulation of PTPRO decreases inflammatory cell infiltration and related cytokine/chemokine levels in HS. a Representative images of myeloperoxidase (MPO) immunofluorescence staining in the lung of HS rats were shown. Magnification: 400 × . Scale = 50 μm. b MPO activity in the lung tissues of HS rats was detected with the MPO kit. c Relative mRNA levels of pro-inflammatory cytokines TNF-α and IL-6 were detected by RT-qPCR. d The levels of TNF-α and IL-6 in bronchoalveolar lavage fluid (BALF) were detected with ELISA. e Relative mRNA levels of chemokine MCP-1, MIP-2, and KC in the lung tissues. f The levels of MCP-1, MIP-2, and KC in BALF were detected with ELISA. g BALF cell counts including total leukocyte, neutrophils, and macrophage. Values are means (n = 6) ± SD. *P < 0.05, **P < 0.01

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