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Table 3 Multivariable logistic regression analyses to predict high probability of ASCVD risk

From: Sarcopenia is associated with cardiovascular risk in men with COPD, independent of adiposity

Variables

All

Mild airflow limitationd

Moderate to very severe airflow limitatione

OR

95% CI

P-value

OR

95% CI

P-value

OR

95% CI

P-value

Age, years

1.56

1.44–1.681

< 0.001

1.55

1.38–1.73

< 0.001

1.59

1.42–1.77

< 0.001

BMI, kg/m2

1.11

0.91–1.350

0.295

1.21

0.88–1.64

0.21

1.06

0.81–1.39

0.683

Fat mass index, kg/m2*

0.93

0.67–1.303

0.686

0.91

0.57–1.47

0.704

0.95

0.58–1.57

0.846

Central obesitya

0.84

0.38–1.884

0.677

0.86

0.25–3.00

0.818

0.78

0.24–2.37

0.655

Current smoking

3.74

2.06–6.779

< 0.001

6.85

2.43–19.31

< 0.001

3.06

1.33–6.71

0.005

Regular exerciseb

1.01

0.57–1.787

0.969

0.76

0.33–1.76

0.516

1.26

0.56–2.85

0.582

Hypertension

8.42

4.52–15.69

< 0.001

11.64

4.58–29.60

< 0.001

8.98

3.73–21.63

< 0.001

Diabetes mellitus

13.77

6.40–29.50

< 0.001

18.06

5.72–57.06

< 0.001

16.06

5.38–47.92

< 0.001

Hyper-LDL cholesterolemia

3.11

1.22–7.92

0.018

5.60

1.42–22.02

0.014

2.20

0.60–8.07

0.237

Hypo-HDL cholesterolemia

3.03

1.71–5.36

< 0.001

3.48

1.50–8.08

0.004

2.77

1.24–6.22

0.013

FEV1, L

1.38

0.82–2.33

0.231

1.33

0.37–4.77

0.664

1.04

0.40–2.70

0.937

Sarcopeniac

2.32

1.05–5.15

0.039

1.93

0.41–9.15

0.41

2.97

1.06–8.36

0.039

  1. ASCVD atherosclerotic cardiovascular disease, BMI body mass index, LDL low-density lipoprotein, HDL high-density lipoprotein, FEV1 forced expiratory volume in 1 s, OR odds ratio, CI confidence interval
  2. *Fat mass index was calculated by dividing each participant’s fat mass (kg) by square of height (m) (kg/m2)
  3. aCentral obesity was defined as waist circumference ≥ 90 cm in men
  4. bRegular exercise was defined as > 20 min per session, at least 3 times per week (n = 702)
  5. cSarcopenia was defined as sarcopenia index < 0.774
  6. dFEV1 ≥ 80% of predicted value
  7. eFEV1 < 80% of predicted value
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Respiratory Research

ISSN: 1465-993X

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