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Table 2 Multiple linear regression analyses of ASCVD risk

From: Sarcopenia is associated with cardiovascular risk in men with COPD, independent of adiposity

Variables All Mild airflow limitationd Moderate to very severe airflow limitatione
Estimated SE P-value Estimated SE P-value Estimated SE P-value
Age, years 0.78 0.03 < 0.001 0.93 0.04 < 0.001 0.71 0.03 < 0.001
BMI, kg/m2 − 0.01 − 0.23 0.816 0.01 0.25 0.805 − 0.01 − 0.46 0.647
Fat mass index, kg/m2* 0.01 0.08 0.939 0.01 0.27 0.790 − 0.01 − 0.37 0.710
Central obesitya − 0.01 − 0.43 0.670 0.03 1.08 0.281 − 0.04 − 1.43 0.155
Current smoking 3.19 0.54 < 0.001 4.40 0.80 < 0.001 2.61 0.70 < 0.001
Regular exerciseb − 0.03 − 1.49 0.136 − 0.02 − 0.49 0.627 − 0.04 − 1.43 0.153
Hypertension 5.29 0.53 < 0.001 6.16 0.77 < 0.001 4.78 0.71 < 0.001
Diabetes mellitus 9.02 0.68 < 0.001 9.83 1.03 < 0.001 7.94 0.89 < 0.001
Hyper-LDL cholesterolemia 0.02 0.71 0.482 2.50 1.20 0.037 − 0.02 − 0.82 0.416
Hypo-HDL cholesterolemia 2.70 0.53 < 0.001 2.65 0.76 0.001 3.25 0.73 < 0.001
FEV1, L 0.01 0.15 0.885 0.01 − 0.01 0.627 0.03 0.83 0.405
Sarcopeniac 3.63 0.77 < 0.001 2.63 1.16 0.025 4.29 1.02 < 0.001
  1. BMI, body mass index; FMI, fat mass index; LDL, low-density lipoprotein; HDL, high-density lipoprotein; FEV1, forced expiratory volume in 1 s; SE standard error
  2. *Fat mass index was calculated by dividing each participant’s fat mass (kg) by square of height (m) (kg/m2)
  3. aCentral obesity was defined as waist circumference ≥ 90 cm in men
  4. bRegular exercise was defined as > 20 min per session, at least 3 times per week (n = 702)
  5. cSarcopenia was defined as sarcopenia index < 0.774
  6. dFEV1 ≥ 80% of predicted value
  7. eFEV1 < 80% of predicted value