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Table 2 Patient vital parameters

From: Effect of pediatric ventilation weaning technique on work of breathing

 

Baseline

CPAP/PS

PC-A/C

Baseline

PS -2cmH2O

PS -4cmH2O

PS -6cmH2O

Clinical parameters

 Comfort score

12 (11–15)

11 (11–14)

12 (11–13)

11 (11–14)

11 (11–14)

11 (11–14)

11 (11–14)

 Heart rate (beats/min)

138 (123–149)

135 (122–149)

138 (116–150)

134 (117–144)

134 (119–142)

130 (114–149)

133 (117–150)

 Peripheral saturation (%)

98 (95–99)

97 (95–98)

98 (96–98)

97 (95–98)

97 (95–98)

96 (94–98)

97 (96 -100)

 Respiratory rate (/min)

37 (26–48)

35 (22–48)

32 (23–43)*

37 (21–48)

36 (23–53)*

37 (30–53)*

35 (27–53)

Respiratory parameters

 Expired tidal volume (ml)

41.1 (27.9–82.9)

41.9 (26.2–85.7)

43.8 (26.1–88.2)

41.1 (24.8–79.9)

38.2 (22.2–69.6)*

34.6 (23.7–74.8)*

36.5 (28.2–73.4)

 End tidal CO2 (mmHg)

49.4 (45.9–54.5)

49.05 (43.7–54.9)

48.8 (45.1–53.4)

49.7 (44.8–52.5)

49.3 (45.6–53.5)

49.4 (44.7–56.3)

53.0 (46.7–55.8)*

 Tinsp

0.50 (0.43–0.67)

0.52 (0.39–0.69)

0.63 (0.44–0.73)*

0.52 (0.40–0.76)

0.49 (0.38–0.68)*

0.51 (0.41–0.63)

0.53 (0.43–0.69)

 RSBI

0.88 (0.33–1.64)

0.78 ( 0.31–1.70)

0.61 (0.29–1.50)*

0.80 (0.28–1.74)

1.00 (0.33–2.09)*

1.10 (0.40–2.09)

0.88 (0.36–2.07)*

Ventilator settings

 Fraction inspired oxygen (%)

30 (26–39)

30 (26–39)

30 (26–39)

30 (25–40)

30 (27–40)

30 (27–40)

30 (27–40)

 PEEP (cmH2O)

6 (5–6)

6 (5–6)

6 (5–6)

6 (5–6)

6 (5–6)

6 (5–6)

6 (5–6)

 PS (cmH2O)1

14 (12–16)

14 (12–16)

14 (12–16)

14 (12–16)

12 (10–14)

10 (8–12)

8 (6–10)

Metrics of oxygenation and ventilation

 PaO2 (mmHg)

76.51 (66.68–87.76)

74.93 (66.54–85.89)

76.51 (67.21–86.26)

No blood samples withdrawn

 PaCO2 (mmHg)

50.10 (56.25–46.50)

50.18 (45.00–5.28)

51.75 (47.25–54.98)

 Oxygenation index

4.92 (3.79–6.03)

4.33 (3.72–5.82)

4.63 (3.79–5.74)

 PF ratio

257 (181–295)

228 (185–278)

249 (192–287)

  1. Data is compared to the baseline or the previous step in the stepwise reduction of the amount of pressure support. No blood samples were withdrawn during the downgrading of pressure support. Data is shown as median (IQR). Statistic test used is the Wilcoxon signed rank test. *p < 0.05
  2. 1Set pressure support or the applied pressure above PEEP when on pressure regulated ventilation