Table 1 Characteristics of patients with anti-GM-CSF autoantibodies
N | Sex F/M | Seen in NIH | Age at sampling (years) Median [range] | Anti-GM-CSF aB level (MMAU) Mean ±SD | ||
|---|---|---|---|---|---|---|
PAP alone | 15 | 9/6 | 11/15 | 48.1 [30.3–66.4] | 495±464 | 6 Rituximab 2 Lung transplant |
Cryptococcus infection alone | 15 | 10/5 | 5/15 | 35.4 [20.4–75] | 197±159 | 4 C neoformans 6 C. gattii 5 undetermined |
Nocardia infection alone | 5 | 2/3 | 3/5 | 52.3 [43.7–62.4] | 430±493 | 1 lung only 4 lung +brain |
PAP+ cryptococcus infection | 3 | 1/2 | 3 | 21/44/51 | 2 C. neoformans 1 C. gattii | |
PAP+ Nocardia infection | 2 | 0/2 | 1 | 44/NA | ||
Crypto + Nocardia infection | 1 | 1/0 | 0 | 60 |