Fig. 6
(GPs’ PCLS): No role of EP1–4-receptors in PDGF-BB-induced bronchoconstriction. A Inhibition of EP1-receptors by SC51322: (◆) no pre-treatment/100 nM PDGF-BB (n = 6); (◇) pre-treatment with 1 µM SC513222/100 nM PDGF-BB (n = 6). B Inhibition of EP2-receptors by PF0441 (◆) no pre-treatment/100 nM PDGF-BB (n = 5); (◇) pre-treatment with 1 µM PF0441/100 nM PDGF-BB (n = 5). C Inhibition of EP3-receptors by L798106: (◆) no pre-treatment/100 nM PDGF-BB (n = 5); (◇) pre-treatment with 1 µM L798106/100 nM PDGF-BB (n = 5). D Inhibition of EP4-receptors by L161982 (◆) no pre-treatment/100 nM PDGF-BB (n = 6); (◇) pre-treatment with 1 µM L161982/100 nM PDGF-BB (n = 6). A–D Statistics was performed by a LMM. p < 0.05 are considered as significant: *p < 0.05, **p < 0.01 and ***p < 0.001