Skip to main content
Fig. 4 | Respiratory Research

Fig. 4

From: Platelet-derived growth factor (PDGF)-BB regulates the airway tone via activation of MAP2K, thromboxane, actin polymerisation and Ca2+-sensitisation

Fig. 4

(GPs’ PCLS): Activation of MAP2K-signalling in PDGF-BB-induced bronchoconstriction. A Inhibition of MAP2K by PD98059 (◆) no pre-treatment/100 nM PDGF-BB (n = 4); (◇) pre-treatment with 50 µM PD98059/100 nM PDGF-BB (n = 4). B Inhibition of MAP2K by U0126 (◆) no pre-treatment/100 nM PDGF-BB (n = 4); (○) pre-treatment with 5 µM U0126/100 nM PDGF-BB (n = 4). A/B Statistics was performed by a LMM. p < 0.05 are considered as significant: *p < 0.05, **p < 0.01 and ***p < 0.001

Back to article page

Respiratory Research

ISSN: 1465-993X

Contact us