Table 2 Methyl subgroup comparisons (PARDS only)
From: Multi-omic characterization of pediatric ARDS via nasal brushings
Subgroup 1 (n = 12) | Subgroup 2 (n = 21) | p-value | ||
|---|---|---|---|---|
(n = 11) | (n = 9) | |||
Age | Median (IQR) | 5.2 (3.5 to 9.9) | 6.8 (3.0 to 10.3) | 0.79 |
Sex | Female | 2 (18.2) | 4 (44.4) | 0.336 |
Male | 9 (81.8) | 5 (55.6) | ||
Race | White | 11 (100.0) | 6 (66.7) | 0.074 |
Non-White | 3 (33.3) | |||
Genetic Synd. or D.D | False | 7 (63.6) | 2 (22.2) | 0.092 |
True | 4 (36.4) | 7 (77.8) | ||
Baseline lung disease | False | 4 (36.4) | 7 (77.8) | 0.092 |
True | 7 (63.6) | 2 (22.2) | ||
Immunocompromised | False | 11 (100.0) | 4 (44.4) | 0.008 |
True | 5 (55.6) | |||
Highest PELOD2 | Median (IQR) | 11.0 (10.5 to 12.0) | 12.0 (11.0 to 13.0) | 0.227 |
Highest PARDS category | None | 1 (9.1) | 0 (0.0) | 1 |
Mild | 2 (18.2) | 2 (22.2) | ||
Moderate | 6 (54.5) | 5 (55.6) | ||
Severe | 2 (18.2) | 2 (22.2) | ||
Viral infection | False | 4 (36.4) | 5 (55.6) | 0.653 |
True | 7 (63.6) | 4 (44.4) | ||
Any corticosteroids | No | 3 (27.3) | 5 (55.6) | 0.362 |
Yes | 8 (72.7) | 4 (44.4) | ||
Ventilator free days | Median (IQR) | 20.4 (13.0 to 24.0) | 17.9 (0.0 to 18.9) | 0.159 |
PICU days | Median (IQR) | 15.0 (10.0 to 23.5) | 17.0 (15.0 to 90.0) | 0.285 |
Hospital days | Mean (SD) | 31.5 (28.3) | 87.6 (75.2) | 0.034 |
Mortality | Survived | 11 (100.0) | 6 (66.7) | 0.074 |
Died | 3 (33.3) |