From: Characterization of the PF-ILD phenotype in patients with advanced pulmonary sarcoidosis
 | N | Univariate analysis for overall mortality and lung transplantation | Multivariate analysis for overall mortality and lung transplantation | |||||
---|---|---|---|---|---|---|---|---|
HR | 95% CI | P-value | HR | 95% CI | P-value | |||
Age | 106 | 1.0 | 1.0–1.1 | 0.127 |  |  |  | |
Gender (male) | 106 | 1.6 | 0.5–4.8 | 0.437 |  |  |  | |
Ethnicity: white | 96 | 0.4 | 0.1–1.1 | 0.070 |  |  |  | |
Smoking | Ex | 100 | 1.5 | 0.5–4.2 | 0.441 |  |  |  |
Current | 100 | 5.0 | 0.6–38.2 | 0.124 |  |  |  | |
CPI | 104 | 1.1 | 1.0–1.1 | 0.049 | 1.0 | 1.0–1.1 | 0.256 | |
PH | 106 | 3.8 | 1.0–14.3 | 0.047 | 4.6 | 1.1–20.3 | 0.042 | |
PF-ILD | 94 | 4.5 | 1.6–12.5 | 0.004 | 4.5 | 1.5–13.7 | 0.008 | |
Scadding stage IV | 100 | 1.5 | 0.5–4.0 | 0.451 |  |  |  | |
Total disease extension | 106 | 1.0 | 1.0–1.0 | 0.438 |  |  |  | |
% Fibrosis | 106 | 1.0 | 1.0–1.1 | 0.062 |  |  |  | |
% Groundglass | 106 | 1.0 | 1.0–1.0 | 0.090 |  |  |  | |
% Other pattern | 106 | 1.0 | 1.0–1.0 | 0.761 |  |  |  | |
MPA/AAD ratio | 103 | 3.2 | 0.2–58.0 | 0.429 |  |  |  | |
Emphysema | 106 | 1.0 | 0.3–3.1 | 0.987 |  |  |  | |
Traction bronchiectasis | 106 | 1.3 | 0.5–3.3 | 0.627 |  |  |  | |
UIP like pattern | 106 | 9.8 | 2.6–36.6 | 0.001 | 13.1 | 3.1–54.6 | < 0.001 | |
MUC5B; carriers of T allele | 106 | 0.6 | 0.2–2.1 | 0.442 |  |  |  | |
Walsh poor prognosis | 106 | 22.6 | 0.0–190 | 0.465 |  |  |  |