Table 3 Characteristics of patients with PF-ILD versus non PF-ILD at baseline (DLCO < 50% of pred.)
From: Characterization of the PF-ILD phenotype in patients with advanced pulmonary sarcoidosis
|  | PF-ILD (n = 14) | Non PF-ILD (n = 80) | P-value | |
|---|---|---|---|---|
Age | 52 ± 12 | 49 ± 13 | NS | |
Male | 10 (71) | 51 (64) | NS | |
Ethnicity | White | 7 (50) | 51 (64) | NS |
Non-white | 4 (29) | 23 (29) | ||
Unknown | 3 (21) | 6 (7) | ||
Smoking history | Never | 5 (36) | 20 (25) | NS |
Former | 9 (64) | 37 (46) | ||
Current | 0 | 18 (23) | ||
Unknown | 0 | 5 (6) | ||
CPI | 48 ± 14 | 47 ± 8 | NS | |
PH | 4 (29) | 8 (10) | NS | |
Total Disease extent | 70; 48–90 | 73; 30–89 | NS | |
% fibrosis | 33; 18–37 | 8; 0–20 | < 0.001 | |
% groundglass | 14; 5–25 | 25; 3–62 | NS | |
% other pattern | 12; 5–18 | 7; 0–24 | NS | |
MPAd/AAd Ratio | 1.0; 0.9–1.1 | 1.0; 0.9–1.1 | NS | |
Emphysema | 3 (21) | 16 (20) | NS | |
Traction bronchiectasis | 13 (93) | 37 (46) | 0.001 | |
UIP like pattern | 1 (7) | 3 (4) | NS | |
MUC5B; rs35705950 carriers of T allele (genotype GT or TT) | 3 (21) | 18 (23) | NS | |
Deaths/lung transplantation | 6 (43) | 10 (13) | 0.013 | |