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Fig. 1 | Respiratory Research

Fig. 1

From: Association of childhood BMI trajectory with post-adolescent and adult lung function is mediated by pre-adolescent DNA methylation

Fig. 1

Path analysis model showing DNAm at 10 years as the mediator between the association of BMI trajectory at earlier childhood and lung function parameters (FEV1, FVC, FEV1/FVC ratio) at post-adolescence. a Effects of BMI-trajectories on methylation of CpGs, controlled for secondhand smoking status before 10 years. b Effects of DNAm on the lung function, controlled for BMI trajectories, socio-economic status (SES), active smoking status at 18, height at 18 years, pubertal events (age at onset of voice deepening in males and age at onset of menarche in females). c Direct effects of BMI trajectories on lung function parameters

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