Metabolomics of bronchoalveolar lavage in children with persistent wheezing

Respiratory Research

Table 2 The increased thirteen metabolites in children with PW relative to control group

Metabolites	Children with PW^#	Control group^#	VIP	P value
Choline	151.396 ± 139.655	79.876 ± 67.897	1.745	0.016*
Oleamide	0.910 ± 1.272	0.069 ± 0.079	2.850	0.001**
Nepetalactam	0.465 ± 0.701	0.068 ± 0.369	2.327	0.009**
Butyrylcarnitine	0.865 ± 0.735	0.450 ± 0.524	1.911	0.015*
l-Palmitoylcarnitine	0.079 ± 0.158	0.007 ± 0.009	2.760	0.018*
PC (16:0/16:0)	41.952 ± 44.008	22.337 ± 15.756	1.705	0.027*
Palmitoylethanolamide	0.680 ± 0.941	0.047 ± 0.055	2.831	0.001**
PC (22:2(13Z, 16Z)/14:0)	4.856 ± 5.948	1.217 ± 1.148	2.432	0.002**
PC (16:0/14:0)	11.616 ± 19.959	2.398 ± 3.296	1.340	0.018*
PC (22:4(7Z, 10Z, 13Z, 16Z)/14:0)	2.238 ± 2.758	0.911 ± 0.937	1.948	0.017*
PC (18:1(11Z)/15:0)	0.555 ± 0.661	0.116 ± 0.119	1.723	0.028*
PC (18:3(6Z, 9Z, 12Z)/18:0)	0.427 ± 4.011	0.148 ± 0.671	1.945	0.030*
PC (20:2(11Z, 14Z)/14:0)	3.203 ± 25.929	0.672 ± 5.623	2.736	0.002**

^#Data was presented with mean ± standard deviation. PC = phosphatidylcholines; PW = persistent wheezing; VIP = variable importance in the projection. *P < 0.05, **P < 0.01

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