Skip to main content
Fig. 4 | Respiratory Research

Fig. 4

From: Increased susceptibility to organic dust exposure-induced inflammatory lung disease with enhanced rheumatoid arthritis-associated autoantigen expression in HLA-DR4 transgenic mice

Fig. 4

ODE-induced airway inflammatory response is increased in the setting of collagen-induced arthritis (CIA) in DR4 mice. A Schematic of experimental design. Bar graphs in B–D depict mean (+ SD) number of cells and levels of cytokines/chemokines from bronchoalveolar lavage fluid (BALF) and lung homogenates in designated treatment groups. B BALF total cells, neutrophils, macrophages, and lymphocytes are enumerated. C BALF levels of TNF-⍺, IL-6, and CXCL1 and D lung levels of fibronectin and IL-33, as determined by ELISA. N = 5–7 mice/group (BALF) and N = 3–5 (Lung). Statistical differences versus respective saline-treated mice are marked by #p < 0.05, ##p < 0.01, ####p < 0.0001. Lines denote difference between groups (**p < 0.01, ***p < 0.001, ****p < 0.0001)

Back to article page

Respiratory Research

ISSN: 1465-993X

Contact us