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Fig. 1 | Respiratory Research

Fig. 1

From: Increased susceptibility to organic dust exposure-induced inflammatory lung disease with enhanced rheumatoid arthritis-associated autoantigen expression in HLA-DR4 transgenic mice

Fig. 1

ODE-induced airway inflammatory response is increased in HLA-DR-transgenic mice. A Schematic of experimental design; Tg = Transgenic. Bar graphs in panels B–D depict mean + SD of cells and cytokines/chemokines from bronchoalveolar lavage fluid (BALF) and lung homogenates corresponding to indicated treatment groups. B BALF total cells, neutrophils, macrophages, and lymphocytes are enumerated. C BALF levels of TNF-⍺, IL-6, and CXCL1 and D lung levels of fibronectin and IL-33 determined by ELISA. N = 5 mice/group. Statistical differences versus saline treated mice are depicted by: #p < 0.05, ##p < 0.01, ###p < 0.001, ####p < 0.0001. Brackets between groups represents significant gene-ODE interaction (P-interaction [int])

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Respiratory Research

ISSN: 1465-993X

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