Score | Cohort | Stratum | Unadjusted | Adjusted | |||
---|---|---|---|---|---|---|---|
HR (95% CI) | p | HR (95% CI) | p | c-index | |||
IPF score | COPDGene test set | All | 1.3 (0.71–2.3) | 0.41 | 1.3 (0.7–2.3) | 0.44 | 0.63 |
ILA | 1.3 (0.47–3.8) | 0.6 | 1.2 (0.44–3.6) | 0.68 | 0.66 | ||
non-ILA | 1.2 (0.57–2.4) | 0.67 | 1.2 (0.58–2.4) | 0.63 | 0.61 | ||
ECLIPSE | All | 1.3 (0.77–2.1) | 0.36 | 1.2 (0.75–2) | 0.4 | 0.56 | |
ILA | 2.2 (0.49–10) | 0.3 | 2.6 (0.54–13) | 0.23 | 0.54 | ||
non-ILA | 1.2 (0.72–2.1) | 0.47 | 1.2 (0.7–2) | 0.54 | 0.56 | ||
ILA score [IPF transcripts] | COPDGene test set | All | 1.4 (1.2–1.7) | 3.60E-05 | 1.3 (1.1–1.6) | 0.0012 | 0.64 |
ILA | 1 (0.64–1.6) | 0.99 | 0.9 (0.53–1.5) | 0.69 | 0.66 | ||
non-ILA | 1.6 (1.3–2) | 2.50E-06 | 1.6 (1.3–2) | 4.00E-05 | 0.62 | ||
ECLIPSE | All | 1.3 (1.1–1.4) | 0.003 | 1.2 (1–1.4) | 0.023 | 0.6 | |
ILA | 1.2 (0.78–1.7) | 0.47 | 1.1 (0.67–1.7) | 0.82 | 0.52 | ||
non-ILA | 1.3 (1.1–1.5) | 0.006 | 1.2 (1–1.4) | 0.027 | 0.59 |