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Table 1 Clinical and demographic characteristics of patients with community-acquired pneumonia with and without acute respiratory distress syndrome

From: Metabolomics profile in acute respiratory distress syndrome by nuclear magnetic resonance spectroscopy in patients with community-acquired pneumonia

Variables

CAP with ARDS (n = 43)

CAP without ARDS (n = 45)

Male sex

30 (69.8)

30 (66.7)

Age (years)

63.9 ± 12.4

60.8 ± 10.8

Smokers

19 (44.2)

19 (42.6)

Underlying diseases

  

 Cardiovascular disease

25 (58.1)

20 (44.4)

 Diabetes mellitus

20 (46.5)

12 (26.7)

 Cerebrovascular disease

3 (7.0)

1 (2.2)

 Chronic kidney disease

2 (4.7)

6 (13.3)

PSI score

20 (10–30)

10 (0–20)

APACHE II score

12 (10–18)

6 (3.0–9.3)

Laboratory results

  

 WBC (× 10^9/L)

10.2 (5.9–13.1)

7.6 (5.5–9.5)

 LDH (µ/L)

373 (259.6–502.0)

260 (221.2–354.5)

 IL-6 (µg/L)

208.3 (97.4–1783.9)

46.7 (15.5–127.4)

 IL-10 (µg/L)

8.3 (5.2–29.1)

3.3 (2.1–6.1)

 LAC (mmol/L)

2.4 (1.8–4.0)

1.8 (1.3–2.7)

 CRP (mg/dL)

183 (146–215)

94.7 (57.3–151.5)

 PCT (ng/mL)

5.7 (0.9–18.3)

0.2 (0.1–0.7)

Oxygen therapy and respiratory support

  

 Nasal cannula

18 (41.8)

45 (100.0)

 Mask and/or HFNO

5 (11.6)

0 (0.0)

 Noninvasive ventilation

8 (18.6)

0 (0.0)

 Invasive mechanical ventilation

12 (27.9)

0 (0.0)

Outcome

  

 Death

7 (16.3)

0 (0.0)

 Survival

36 (83.7)

45 (1.0)

  1. CAP community-acquired pneumonia, ARDS acute respiratory distress syndrome, PSI pneumonia severity index, APACHE II acute physiology and chronic health evaluation II scores, WBC white blood cell, LDH lactate dehydrogenase, IL interleukin, LAC lactic acid, CRP c-reactive protein; PCT procalcitonin, HFNO high-flow nasal oxygen