Table 1 Dynamic urinary proteome changes in the cigarette smoke-induced COPD rats
From: Proteome analysis of urinary biomarkers in a cigarette smoke-induced COPD rat model
Accession | Protein names | week 2 | week 4 | week 8 | Human orthologs |
|---|---|---|---|---|---|
P23764 | Glutathione peroxidase 3 | 3.68 | 2.14 | 1.75 | P22352 |
P01015 | Angiotensinogen | 2.40 | 1.94 | None | |
P02761 | Major urinary protein | 2.39 | 2.52 | None | |
Q9WUW9 | Sulfotransferase 1C2A | 2.20 | 1.62 | O00338 | |
P29598 | Urokinase-type plasminogen activator | 1.98 | 1.70 | P00749 | |
P17475 | Alpha-1-antiproteinase | 1.81 | 1.60 | P01009 | |
P48199 | C-reactive protein | 1.73 | 1.72 | P02741 | |
P07151 | Beta-2-microglobulin | 1.65 | 1.80 | P61769 | |
Q99PS8 | Histidine-rich glycoprotein | 0.41 | 0.20 | None | |
P22282 | Cystatin-related protein 1 | 0.41 | 3.61 | None | |
P02780 | Secretoglobin family 2A member 2 | 0.47 | 3.36 | None | |
P22283 | Cystatin-related protein 2 | 0.47 | 3.36 | None | |
Q9JHB9 | Secretoglobin family 2A member 1 | 0.48 | 3.11 | None | |
P02782 | Prostatic steroid-binding protein C1 | 0.44 | 3.09 | None | |
P08592 | Amyloid-beta precursor protein | 0.57 | 0.61 | P05067 | |
P01681 | Ig kappa chain V region S211 | 3.57 | 0.38 | None | |
Q66H12 | Alpha-N-acetylgalactosaminidase | 2.50 | 0.26 | P17050 | |
P00758 | Kallikrein-1 | 1.56 | 0.55 | None | |
P14841 | Cystatin-C | 3.70 | P01034 | ||
P50430 | Arylsulfatase B | 3.61 | P15848 | ||
Q63621 | Interleukin-1 receptor accessory protein | 2.47 | Q9NPH3 | ||
Q68FP1 | Gelsolin | 2.01 | P06396 | ||
P31211 | Corticosteroid-binding globulin | 1.90 | None | ||
Q9Z0W7 | Chloride intracellular channel protein 4 | 1.88 | Q9Y696 | ||
Q01177 | Plasminogen | 1.80 | P00747 | ||
Q9JJ40 | Na (+)/H (+) exchange regulatory cofactor NHE-RF3 | 1.68 | Q5T2W1 | ||
P01048 | T-kininogen 1 | 1.68 | None | ||
Q03626 | Murinoglobulin-1 | 1.65 | None | ||
Q64240 | Protein AMBP | 1.61 | P02760 | ||
P36953 | Afamin | 1.60 | P43652 | ||
P20611 | Lysosomal acid phosphatase | 1.59 | P11117 | ||
Q9QX79 | Fetuin-B | 1.59 | None | ||
Q642A7 | Protein FAM151A | 1.58 | Q8WW52 | ||
P02651 | Apolipoprotein A-IV | 1.57 | None | ||
Q920A6 | Retinoid-inducible serine carboxypeptidase | 1.51 | Q9HB40 | ||
P13432 | SMR1 protein | 0.64 | None | ||
P42854 | Regenerating islet-derived protein 3-gamma | 0.32 | Q06141 | ||
P29534 | Vascular cell adhesion protein 1 | 0.19 | P19320 | ||
B5DFC9 | Nidogen-2 | 0.44 | Q14112 | ||
O35217 | Multiple inositol polyphosphate phosphatase 1 | 1.90 | Q9UNW1 | ||
O35763 | Moesin | 1.68 | P26038 | ||
P00762 | Anionic trypsin-1 | 4.66 | P07478 | ||
P01836 | Ig kappa chain C region, A allele | 0.66 | None | ||
P04937 | Fibronectin | 1.81 | P02751 | ||
P08649 | Complement C4 | 0.43 | P0C0L4 | ||
P24090 | Alpha-2-HS-glycoprotein | 0.39 | None | ||
P48500 | Triosephosphate isomerase | 0.48 | P60174 | ||
Q4QQW8 | Putative phospholipase B-like 2 | 2.65 | Q8NHP8 | ||
Q5M876 | N-acyl-aromatic-l-amino acid amidohydrolase | 1.78 | Q96HD9 | ||
Q64230 | Meprin A subunit alpha | 1.69 | Q16819 | ||
Q6P7A9 | Lysosomal alpha-glucosidase | 0.47 | P10253 | ||
Q80W57 | Broad substrate specificity ATP-binding cassette transporter ABCG2 | 2.41 | Q9UNQ0 | ||
P01835 | Ig kappa chain C region, B allele | 0.54 | P0DOX7 | ||
P02781 | Prostatic steroid-binding protein C2 | 4.03 | None | ||
P06866 | Haptoglobin | 2.54 | P00739 | ||
P06882 | Thyroglobulin | 0.37 | P01266 | ||
P11951 | Cytochrome c oxidase subunit 6C-2 | 0.61 | P09669 | ||
P15978 | Class I histocompatibility antigen, Non-RT1.A alpha-1 chain | 2.80 | P01889 | ||
P16391 | RT1 class I histocompatibility antigen, AA alpha chain | 0.46 | P04439 | ||
P25236 | Selenoprotein P | 0.22 | P49908 | ||
P28826 | Meprin A subunit beta | 0.58 | Q16820 | ||
P31044 | Phosphatidylethanolamine-binding protein 1 | 2.69 | P30086 | ||
P36374 | Prostatic glandular kallikrein-6 | 1.58 | None | ||
P36376 | Glandular kallikrein-12, submandibular/renal | 1.78 | None | ||
P97546 | Neuroplastin | 0.63 | Q9Y639 | ||
Q09030 | Trefoil factor 2 | 0.02 | Q03403 | ||
Q5FVH2 | 5′-3′ exonuclease PLD3 | 0.58 | Q8IV08 | ||
Q5U2Q3 | Ester hydrolase C11orf54 homolog | 0.31 | Q9H0W9 | ||
Q62839 | Golgin subfamily A member 2 | 2.73 | Q08379 | ||
Q63678 | Zinc-alpha-2-glycoprotein | 2.68 | None | ||
Q6AYR9 | Tetraspanin-1 | 3.48 | O60635 | ||
Q6AYS7 | Aminoacylase-1A | 0.44 | Q03154 | ||
Q6IRK9 | Carboxypeptidase Q | 0.62 | Q9Y646 | ||
Q6TUD4 | Protein YIPF3 | 0.60 | Q9GZM5 | ||
Q8VD89 | Ribonuclease pancreatic gamma-type | 5.01 | None | ||
Q99J86 | Attractin | 3.02 | O75882 | ||
Q9JHY1 | Junctional adhesion molecule A | 0.57 | Q9Y624 | ||
Q9JI85 | Nucleobindin-2 | 2.59 | P80303 | ||
H1UBN0 | Copine-7 | 0.18 | None |